Petrovax Pharm launches Polyoxidonium® in drops

Moscow, July 10, 2025 — Petrovax Pharm launched Polyoxidonium® (azoximer bromide) in its new dosage form of 6 mg drops for topical use. This new product will be available in pharmacies as early as July-August 2025. The new form has been developed for the convenient treatment and prevention of ARVI, influenza, and ENT diseases in adults and children aged 6 months and older[1].

More than 30 million Russians contract ARVI and influenza each year[2]. Children under the age of 5 are particularly vulnerable, suffering an average of 6–8 episodes of respiratory viral infections per year[2].

Experts recommend using immunotropic drugs with proven efficacy in the complex therapy of ARVI and influenza due to the growing resistance of pathogens to etiotropic therapy[3] and also focus on the activation of mucosal immunity—the first barrier protecting against viruses and bacteria.

Polyoxidonium® in drops with a dosing pipette attachment has been custom-designed for convenient topical use. The drug facilitates mucosal immune response even in the youngest patients. Unlike other drugs, Polyoxidonium® has detoxifying properties, acting on the pathogenesis of symptoms[4].

According to a study involving more than 16,000 patients[3] Polyoxidonium® in combination therapy for ENT diseases facilitates quick relief of symptoms of ARVI, such as fever, sore throat, nasal congestion and cough. The drug improves health from the first days[5], accelerates the relief of catarrhal symptoms by an average of 1.3 days and protects against recurrent episodes of ARVI for up to 3.5 months[6], [7].

"During the cold season, it is important to use medications with a known cellular mechanism of action and proven immunotropic activity,"
noted[8] Olesya Skorokhodkina, Dr. habil. med, professor, head of the Department of Clinical Immunology and Allergology at the Federal State Budgetary Educational Institution of Higher Education (FSBEI HE) Kazan State Medical University (KSMU), at the conference.

The expert noted that azoximer bromide (Polyoxidonium®) enhances interferon synthesis and activates natural killer cells (NK cells[9]), which is pivotal in fighting viruses.

The properties of azoximer bromide have been confirmed in double-blind placebo-controlled studies and post-marketing studies in Russia and the EU. The research data is presented in more than 350 scientific papers.

Polyoxidonium® is an original medicinal product manufactured by Petrovax Pharm and used in Russia and abroad. Presented as drops, this new dosage form is a convenient and state-of-the-art solution developed with the needs of both patients and physicians (therapists, pediatricians and ENT specialists) in mind, who have long sought this type of product.


1 “Basic Prescribing Information of the medicinal product Polyoxidonium, solution for injection and topical application LP-005312”, July 20, 2021 https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGuid=79ae0a13-d997-4177-8bba-546cd049858d&t=

2 Acute respiratory viral infection (ARVI). https://www.pediatr-russia.ru/information/klin-rek/proekty-klinicheskikh rekomendatsiy/%D0%9E%D0%A0%D0%92%D0%98%20%D0%B4%D0%B5%D1%82%D0%B8%20%D0%A1%D0%9F%D0%A0_1.06.2021.pdf

3 Svistushkin Valery Mikhailovich, Nikiforova Galina Nikolaevna, Eremeeva Ksenia Vladimirovna, Dekhanov Artem Sergeevich, and Kochetkov Petr Alexandrovich. "Capacity of azoximer bromide in the treatment of patients with acute infectious and inflammatory diseases of the upper respiratory tract." Therapeutic Archive 95, issue 11 (22 December 2023): 951–57. https://doi.org/10.26442/00403660.2023.11.202488

4 R. V. Petrov, R. M. Khaitov, A. V. Nekrasov, R. I. Attaulakhanov, N. G. Puchkova, A. S. Ivanova, B. V. Pinegin, K. F. Khamidullina, S. V. Dambaeva, and S. V. Klimova. Polyoxidonium - mechanisms of action and clinical relevance. Medical Immunology (Russia) 2, issue 3 (2000). https://elibrary.ru/item.asp?id=11608350

5 V. P. Vavilova, A. M. Vavilov and A. Kh. Cherkayeva. Possibilities of modern treatment of acute respiratory viral infections in children. Pediatrics. Supplement to Consilium Medicum journal, issue 3 (2015 г.). https://elibrary.ru/item.asp?id=24295061

6 V. P. Vavilova, O. S. Chernyuk, T. A. Karaulnova and N.I. Tarasova New ways of influencing local protective factors in children with pharyngeal lymphoid ring pathology | #06/11 | Attending physician — professional medical publication for physicians. Scientific papers. Journal "Attending physician", issue 6 (June 2011). https://www.lvrach.ru/2011/06/15435224

7 V. P. Vavilova, N. K. Perevoshchikova, A. A. Rizo, S. A. Pavlenko, T. V. Filippova, et al. Application of Russian immunoregulator polyoxidonium in children with lymphopharyngal pathologies//Pediatric Allergology and Immunology. 2005; No. 4; pp. 47-53.

8 https://petrovax.ru/press_centre/news/2025/uspeshnye-metody-bor%27by-s-orvi-i-grippom-obsudili-na-konferentsii-v-kazani/

9 NK cells, natural killer cells belong to special type of lymphocyte that plays a key role in innate immunity.
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