Vaccination against influenza and pneumococcal infection can make a big contribution to the indicators of the national project Demography

In Russia, a series of meetings among the professional medical community on issues of immunization of the adult population, organized by the Russian Society for the Prevention of Non-Communicable Diseases (RSPNCD), has been completed. Vaccination against influenza and pneumococcal infection helps to increase life expectancy and reduce mortality in the elderly and people with chronic diseases (diabetes, cardiovascular and bronchopulmonary diseases). The online events were attended by leading specialists in cardiology, epidemiology, gerontology, and pulmonology from eight federal districts of Russia.

"Vaccination against influenza and pneumococcus plays a huge role in reducing mortality in patients with concomitant diseases, especially in patients with cardiovascular diseases,"
emphasized Oksana Mikhailovna Drapkina, MD, professor, academician of the Russian Academy of Sciences, chief specialist in therapy and general medical practice at the Russian Ministry of Health.

Immunization helps reduce the risk and severity of respiratory illnesses, pneumonia, and complications that can be caused by influenza or pneumococcal disease. This preventive measure can make a significant contribution to the indicators of the national project Demography and the implementation of state programs for active longevity of the population of Russia — these are the conclusions of the final session, which took place on November 19.

Pneumococcal infection is one of the leading infectious causes of death[1]. Most often, pneumonia develops against the background of pneumococcal infection, but other manifestations are also common, such as meningitis, sinusitis, otitis, and others[2].

"Today, vaccines are the most powerful tool in the fight against infections — they save lives. The older the patient, the higher the risk of developing pneumonia due to a respiratory disease. The risk of mortality remains for the next five years after the disease has been suffered,"
noted Sergei Nikolaevich Avdeev, MD, professor, corresponding member of the Russian Academy of Sciences, chief pulmonologist at the Russian Ministry of Health.

Pneumococcal infection and its complications are especially dangerous for people in risk groups. Among them are the elderly, patients suffering from non-communicable diseases: diabetes mellitus, COPD, chronic heart failure, bronchial asthma, as well as smokers[3], [4].

Immunization against influenza reduces the risk of cardiovascular pathologies, the likelihood of contracting COVID-19 and suffering from it in a severe form, reduces the chances of developing Alzheimer’s disease within 4 years from the date of vaccination by 40%, and reduces the frequency of relapses in multiple sclerosis by almost 2 times[5], [6], [7].

Pneumonia does not pass without leaving a trace on the body. The disease has a negative impact on health even after recovery; studies show that the risk of premature death remains increased even a year after the illness[8].

Immunization of the population is the most effective and safe way to protect against the consequences of acute respiratory diseases caused by influenza and pneumococcal infection.

"For each risk group of the population, there is a specific vaccination schedule, which is reflected in the Methodological Recommendations for Vaccination Prevention in Children and Adults. Each regimen begins with the introduction of a conjugate vaccine, to which a polysaccharide vaccine is then added at a certain interval,"
explained Roman Vladimirovich Polibin, PhD, chief epidemiologist at the Russian Ministry of Health.

As effective measures for preventing the development of complications against the background of influenza and pneumococcal infection, experts name the adjuvant vaccines against influenza "Grippol® Plus";, "Grippol® Quadrivalent" and the 13-valent conjugate pneumococcal vaccine "Prevenar® 13", which are characterized by high immunogenicity and a favorable safety profile.


1 Nikolay Ivanovich Briko, Vladimir Andreyevich Korshunov, Kirill Sergeyevich Lomonosov PNEUMOCOCCAL DISEASE IN THE RUSSIAN FEDERATION: STATE OF THE ISSUE // Annals of the Russian Academy of Medical Sciences (RAMS). 2021. No.1

2 Baranov A. A., Namazova L. S., Tatochenko V. K. Pneumococcal infection and associated diseases are a serious problem of modern health care // PF. 2008. No. 1

3 Vila-Corcoles A, Ochoa-Gondar O, Vila-Rovira A, Aragon M, Esteban-Julvez L, Chamorro N, Hospital I, Satue E, Blade J, de Diego C, Gomez-Bertomeu F, Raga X. Incidence and Risk of Pneumococcal Pneumonia in Adults with Distinct Underlying Medical Conditions: A Population-Based Study. Lung. 2020 Jun;198(3):481-489. doi: 10.1007/s00408-020-00349-y. Epub 2020 Apr 6. PMID: 32253492.

4 Shea KM, Edelsberg J, Weycker D, Farkouh RA, Strutton DR, Pelton SI. Rates of pneumococcal disease in adults with chronic medical conditions. Open Forum Infect Dis. 2014 May 27;1(1):ofu024. doi: 10.1093/ofid/ofu024. PMID: 25734097; PMCID: PMC4324183.

5 Bukhbinder AS, Ling Y, Hasan O, Jiang X, Kim Y, Phelps KN, Schmandt RE, Amran A, Coburn R, Ramesh S, Xiao Q, Schulz PE. Risk of Alzheimer's Disease Following Influenza Vaccination: A Claims-Based Cohort Study Using Propensity Score Matching. J Alzheimers Dis. 2022;88(3):1061-1074. doi: 10.3233/JAD-220361. PMID: 35723106; PMCID: PMC9484126.

6 Winkelmann, A., Metze, C., Zettl, U.K. et al. Side effects following vaccination in multiple sclerosis: a prospective, multi-centre cohort study. Sci Rep 13, 14480 (2023).

7 Su W, Wang H, Sun C, Li N, Guo X, Song Q, Liang Q, Liang M, Ding X, Sun Y. The Association Between Previous Influenza Vaccination and COVID-19 Infection Risk and Severity: A Systematic Review and Meta-analysis. Am J Prev Med. 2022 Jul;63(1):121-130. doi: 10.1016/j.amepre.2022.02.008. Epub 2022 Mar 15. Erratum in: Am J Prev Med. 2022 Nov;63(5):874. doi: 10.1016/j.amepre.2022.09.001. PMID: 35410774; PMCID: PMC8920881.

8 Ramirez JA, Wiemken TL, Peyrani P, Arnold FW, Kelley R, Mattingly WA, Nakamatsu R, Pena S, Guinn BE, Furmanek SP, Persaud AK, Raghuram A, Fernandez F, Beavin L, Bosson R, Fernandez-Botran R, Cavallazzi R, Bordon J, Valdivieso C, Schulte J, Carrico RM; University of Louisville Pneumonia Study Group. Adults Hospitalized With Pneumonia in the United States: Incidence, Epidemiology, and Mortality. Clin Infect Dis. 2017 Nov 13;65(11):1806-1812. doi: 10.1093/cid/cix647. PMID: 29020164.
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