The expert drew attention to two studies on using bovhyaluronidase azoximer in chronic prostatitis involving more than 100 men. All of them passed a medical examination, submitted their ejaculate for bacterial inoculation and were divided into two groups according to the analysis results: the first group with bacterial prostatitis and the second group with abacterial one. However, the study showed that, when using molecular genetic methods, harmful bacteria that affect the development of prostatitis had been found in the group including patients with abacterial prostatitis.
The fact is that biofilms did not allow to detect the presence of bacteria, thus interfering with the disease diagnosis. When using bovhyaluronidase azoximer molecules (Longidaza®), the biofilm volume halved, whereas the patients’ condition returned to normal.
The drug facilitated the bacterial prostatitis diagnosis and improved the therapy results due to suppressing edema, improving microcirculation, destroying biofilms, and removing «plugs» in the gland ducts, as well as de-fibrosing the overgrown connective tissue and increasing the bioavailability of antibiotics.
Today, as experts say, the abacterial prostatitis incidence is still dramatically overestimated, whereas bacterial prostatitis remains undiagnosed in almost half of cases, and, consequently, patients do not receive the required therapy.
Patients with chronic prostatitis have fibroplastic changes, the so-called prostatic pelvic pain. Fibrosis is a pathological condition with an excessive growth of connective tissue. This is a normal reaction of the body, aimed at protecting tissues from inflammatory processes. However, if there is too much connective tissue, it can be difficult to make a correct diagnosis, and the treatment outcomes get worse due to reduced penetration of drugs into the inflamed prostate. All of this leads to the process becoming chronic. In addition, fibrosis significantly impairs the prostate gland function and negatively affects urination.
Longidaza® is an enzyme drug that helps reduce inflammation and prevents the development of fibrosis. Its use in urology is quite wide: prostatitis, surgical pathologies, prostatic hyperplasia, prevention of scaring processes, etc.